The DNA Core Facility provides high-throughput DNA sequencing services to all four campuses of the University of Missouri system and external researchers. The facility has performed next generation sequencing services since 2008. Core staff are experienced with RNA/DNA QC techniques, library construction methods, and data generation on Illumina instruments. The facility maintains a NextSeq 500 and two MiSeq instruments, as well as, necessary ancillary equipment. The combined data yield of these instruments allows the DNA Core to provide sequencing capacity for both the small and large project.
The DNA Core currently provides library construction services for several methods.
- Illumina Small RNA Library
- Illumina mRNA Stranded Library(RNA-Seq)
- Clonetech Ultra Low Input RNA Library(RNA-Seq)
- Illumina DNA PCR-free Library
- NEB Whole Genome Bisulfite Sequencing (WGBS)
- NEB Methylated DNA Enrichment Library
- Amplicon Library
- 16S Sequencing
The DNA Core offers free consultation for researchers in the grant application process or project initiation phase. Staff can discuss current technology capabilities, prepare cost estimates, and provide letters of support. Additional literature and information on applications, as well as selected publications, can be obtained from the Illumina website.
Contact the DNA Core for additional information on conducting a sequencing project with the facility.